教育背景

2008年09月～2015年07月 中国农业大学生物化学与分子生物学专业 理学博士

2002年09月～2006年07月 复旦大学生物科学专业 理学学士

工作经历

2023年01月～今 江西科技师范大学  副教授

2015年07月～2022年12月 江西科技师范大学  讲师

研究领域

1、小分子荧光探针的设计合成和应用

2、真菌次级代谢产物的合成及调控机制研究

主要研究成果

主要从事小分子荧光探针的设计合成以及真菌次级代谢产物合成的调控机制研究。近年来，作为项目负责人主持省部级项目3项，横向课题1项，作为项目主要成员参与多项国家自然科学基金项目及省部级项目。目前，以第一通讯作者发表SCI论文20余篇，其中2篇为一区TOP论文。

主要代表学术论文

1、Wenbin Yu, Zhiwei Ouyang, Yufei Zhang, Yi Lu, Changhe Wei, Yayi Tu*, Bin He*. Research progress on the artificial intelligence applications in food safety and quality management, Trends in Food Science & Technology, 2025, 156, 104855.

2、Jianning Dong, Zixing Ye, Yayi Tu*, Congbin Fan*. A novel NIR fluorescent probe targeting mitochondria for the detection of Cys using benzothiocarbonate recognition site, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2025, 325, 125169.

3、Wenbin Yu, Yufei Zhang, Yi Lu, Zhiwei Ouyang, Jiahua Peng, Yayi Tu*, Bin He*. Recent research on the bioactivity of polyphenols derived from edible fungi and their potential in chronic disease prevention, Journal of Functional Foods, 2025, 124, 106627.

4、Wenbin Yu, Zeying Zhao, Yufei Zhang, Yayi Tu*, Bin He*. AozC, a zn(II)2Cys6 transcription factor, negatively regulates salt tolerance in Aspergillus oryzae by controlling fatty acid biosynthesis, Microbial Cell Factories, 2025, 24, 10.

5、Wenbin Yu, Yufei Zhang, Lihua Yao, Jiahua Peng, Yayi Tu*, Bin He*. Research progress on the prevention of tumor by fungal polysaccharides, Trends in Food Science & Technology, 2024, 147, 104422.

6、Yufei Zhang, Wenbin Yu, Yi Lu, Yichuan Wu, Zhiwei Ouyang, Yayi Tu*, Bin He*. Epigenetic regulation of fungal secondary metabolism, Journal of Fungi, 2024, 10, 648.

7、Wenbin Yu, Yufei Zhang, Zhiwei Ouyang, Yayi Tu*, Bin He*. The molecular regulation of microbial metabolism, Frontiers in Cell and Developmental Biology, 2024, 12, 1458625.

8、 Wenbin Yu, Zeying Zhao, Bin Zeng, Yayi Tu*, Bin He*. Alanine supplementation enhancing cordycepin production in Cordyceps militaris via upregulation of Cns2 and Cns3 genes expression levels, Journal of Food and Drug Analysis, 2024, 32, 589-602.

9、Wenbin Yu, Rongqiang Pei, Yufei Zhang, Yayi Tu*, Bin He*. Light regulation of secondary metabolism in fungi, Journal of Biological Engineering, 2023, 17, 57.

10、Jianning Dong, Guowei Lu, Bin He, Yayi Tu*, Congbin Fan*. A novel NIR fluorescent probe for monitoring cysteine in mitochondria of living cells, Arabian Journal of Chemistry, 2023, 16 (6), 104765.

11、Wenbin Yu, Rongqiang Pei, Jingyi Zhou, Bin Zeng, Yayi Tu*, Bin He*. Molecular regulation of fungal secondary metabolism, World Journal of Microbiology and Biotechnology, 2023, 39: 204.

12、Rutao Liang, Xinyue Luo, Yanqing Luo, Fangfang Liu, Zhongyu Hu, Zhenhua Xiong, Yayi Tu*, Congbin Fan*. A highly selective and sensitive fluorescent probe for Zn²⁺ based on diarylethene with a thienyl hydrazide unit, Journal of Photochemistry and Photobiology A-Chemistry, 2023, 445, 115107.

13、Jianning Dong, Yanhua Wang, Congbin Fan, Yayi Tu*, Shouzhi Pu*. Chalcone dye-based fluorescent probe for selective and specific detection of cysteine in lysosomes of living cells, Dyes and Pigments, 2023, 210, 110994.

14、Guowei Lu, Jianning Dong, Congbin Fan, Yayi Tu*, Shouzhi Pu*. A coumarin-based fluorescent probe for specific detection of cysteine in the lysosome of living cells, Bioorganic Chemistry, 2022, 119, 105558.

15、Jianning Dong, Guowei Lu, Yayi Tu*, Congbin Fan*. Recent research progress of red-emitting/nearinfrared fluorescent probes for biothiols, New Journal of Chemistry, 2022, 46, 10995-11020.

16、Yanhua Wang, Guowei Lu, Yayi Tu*, Shouzhi Pu*. A turn-on fluorescent probe for the discrimination of Cys/Hcy and GSH with dual emission signals, Journal of Fluorescence, 2021, 31, 599-607.

17、Xufen Song, Yayi Tu*, Renjie Wang, Shouzhi Pu*. A lysosome-targetable fluorescent probe for simultaneous detection and discrimination of Cys/Hcy and GSH by dual channels, Dyes and Pigments, 2020, 177, 108270.

18、Lihui Zhai, Yayi Tu*, Zhanglin Shi, Shouzhi Pu*. A colorimetric and fluorescent chemosensor based on diarylethene for simultaneous detection and discrimination of biothiols, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2019, 218, 171-177.

19、Lihui Zhai, Zhanglin Shi, Yayi Tu*, Shouzhi Pu*. A dual emission fluorescent probe enables simultaneous detection and discrimination of Cys/Hcy and GSH and its application in cell imaging, Dyes and Pigments, 2019, 165, 164-171.

20、Zhanglin Shi, Yayi Tu*, Renjie Wang, Gang Liu, Shouzhi Pu*. Highly sensitive and selective turn-on fluorescent sensor for dual recognition of Cu²⁺ and CN^- based on a methylquinoline derivative, Dyes and Pigments, 2018, 149, 764-773.